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Physical inactivity is associated with a higher risk for severe COVID-19 outcomes: A study in 48 440 adult patients. Sallis, R., et al. (2021) Level of Evidence : 2b Follow recommendation : 👍 👍 👍 (3/4 thumbs) Type of study : Preventative Topic : Physical activity and COVID-19 - Risk reduction This is a retrospective study assessing the correlation between pre-infection physical activity and severity of COVID-19 infection. A total of 103,337 participants were included. The severity of COVID-19 infection was measured by rate of hospitalisation, admission to ICU, and deaths associated with it. The results showed that of the total sample, 8.6% were hospitalised, 2.4% had to be admitted to ICU, and 1.6% died. Patients who were consistently inactive (did not meet the physical activity guidelines) were a greater odds of been hospitalised, being admitted to ICU, and dying compared to patients who consistently met the physical activity guidelines. These findings were retained even with analyses that adjusted for several confounding variables (e.g. age) - see forest plot below. Disclaimer: This publication was reviewed and assessed by one reviewer only and it reflects their interpretation. Readers should come to their own conclusions by reading the original article. Clinical Take Home Message : Based on what we know today, physical activity appears to reduce the risk of COVID-19 severity. This is important to remember because many of our clients undergo periods of reduced activity due to their upper limb injuries. If possible, we should therefore find alternative exercising strategies that maintain them active whilst avoiding loading of healing tissues. Ideally we would suggest them to follow the physical activity guideline that were discussed in a previous synopsis (See picture below for further information). Following the WHO physical activity guidelines will not only improve prognosis for COVID-19 infection, but also improve wound healing , bone mass density , and mental health status , which is a factor influencing our clients recovery . Open Access URL : http://bjsm.bmj.com/content/early/2021/04/07/bjsports-2021-104080.abstract Abstract Objectives: To compare hospitalisation rates, intensive care unit (ICU) admissions and mortality for patients with COVID-19 who were consistently inactive, doing some activity or consistently meeting physical activity guidelines. Methods: We identified 48 440 adult patients with a COVID-19 diagnosis from 1 January 2020 to 21 October 2020, with at least three exercise vital sign measurements from 19 March 2018 to 18 March 2020. We linked each patient’s self-reported physical activity category (consistently inactive=0–10 min/week, some activity=11–149 min/week, consistently meeting guidelines=150+ min/week) to the risk of hospitalisation, ICU admission and death after COVID-19 diagnosis. We conducted multivariable logistic regression controlling for demographics and known risk factors to assess whether inactivity was associated with COVID-19 outcomes. Results: Patients with COVID-19 who were consistently inactive had a greater risk of hospitalisation (OR 2.26; 95% CI 1.81 to 2.83), admission to the ICU (OR 1.73; 95% CI 1.18 to 2.55) and death (OR 2.49; 95% CI 1.33 to 4.67) due to COVID-19 than patients who were consistently meeting physical activity guidelines. Patients who were consistently inactive also had a greater risk of hospitalisation (OR 1.20; 95% CI 1.10 to 1.32), admission to the ICU (OR 1.10; 95% CI 0.93 to 1.29) and death (OR 1.32; 95% CI 1.09 to 1.60) due to COVID-19 than patients who were doing some physical activity. Conclusions: Consistently meeting physical activity guidelines was strongly associated with a reduced risk for severe COVID-19 outcomes among infected adults. We recommend efforts to promote physical activity be prioritised by public health agencies and incorporated into routine medical care. publications = Total number of papers citing this research supporting = Citation statements supporting the findings mentioning = Neutral citation statements contrasting = Citation statements not supporting the findings

Greater efficacy of a combination of conservative therapies for thumb base OA in individuals with lower radial subluxation – a pre-planned subgroup analysis of the COMBO trial. Deveza, L. A., et al. (2021) Level of Evidence : 2b Follow recommendation : 👍 👍 👍 (3/4 thumbs) Type of study : Prognostic Topic : Thumb osteoarthritis - thumb base radial deviation and treatment response This is a subgroup analysis of a previously published randomised controlled trial . This subgroup analysis aimed at assessing whether base of thumb radial subluxation, Kellgren Lawrence grade (KL), presence of interphalangeal joint OA, and presence of erosive hand OA affected response to conservative treatment. The two treatment types have been previously reported in the trial and included education alone or a combination of multiple conservative treatments . There were a series of outcomes being collected to assess response to treatment with the primary being pain (visual analogue scale - VAS) and function (functional index of hand OA - FIHOA) measured at six weeks. The results showed a multimodal treatment was associated with better outcomes in people with lower levels of thumb base radial deviation. Despite this finding, the improvements were quite heterogeneous and may not be clinically relevant. No other factors appeared to mediate treatment response. Disclaimer: This publication was reviewed and assessed by one reviewer only and it reflects their interpretation. Readers should come to their own conclusions by reading the original article. Clinical Take Home Message : Based on what we know today, lower levels of thumb base subluxation may predict better treatment outcomes in people with thumb OA . Radiologic findings (e.g. erosive OA) do not appear to largely affect treatment. This appears to be supported by previous evidence showing that pain catastrophising (rather than x-ray findings) is associated with pain intensity in thumb OA . An additional factor that appears to mediate treatment response in thumb OA is treatment expectations . In particular, more positive treatment expectations are associated with better treatment outcomes. URL : https://doi.org/10.1016/j.joca.2021.07.010 Abstract Objective: To investigate heterogeneous effects of a combination of conservative therapies compared with an education comparator for thumb base (TB) osteoarthritis (OA) according to clinically relevant characteristics. Methods: Pre-planned subgroup analysis of the COMBO trial (n = 204) which compared a combination of education on self-management and ergonomic principles, a prefabricated neoprene splint, hand exercises, and diclofenac sodium gel, with education alone for radiographic and symptomatic TB OA. Primary outcomes were change in pain (visual analogue scale [VAS], 0–100 mm) and hand function (Functional Index for Hand Osteoarthritis questionnaire, 0–30) from baseline to week-6. Other outcomes were grip and tip-pinch strength and patient's global assessment (PGA) (VAS, 0–100 mm). Possible treatment effect modifiers were the presence of interphalangeal joint pain, erosive hand OA, radiographic thumb carpometacarpal joint subluxation (higher vs equal or lower than the sample mean), and baseline radiographic OA severity (Kellgren Lawrence grade). Linear regression models were fitted, adding interaction terms for each subgroup of interest. Results: The treatment effects of the combined intervention at 6 weeks were greater in participants with lower joint subluxation compared with those with greater subluxation (pain −11.6 [95%CI −22.2, −9.9] and 2.6 [−5.5, 10.7], respectively, difference between the subluxation groups 14.2 units (95% CI 2.3, 26.1), p-value 0.02; and PGA −14.0 [−22.4, −5.5] and 1.5 [−6.2, 9.3), respectively, difference between the subluxation groups 15.5 units (95% CI 4.2, 26.8), p-value 0.03). There was no statistically significant heterogeneity for the other subgroups. Conclusion: A combination of conservative therapies may provide greater benefits over 6 weeks in individuals with lower joint subluxation, although the clinical relevance is uncertain given the wide confidence intervals. Treatment strategies may need to be customized for those with greater joint subluxation. Trial registration number ACTRN 12616000353493. publications = Total number of papers citing this research supporting = Citation statements supporting the findings mentioning = Neutral citation statements contrasting = Citation statements not supporting the findings

Evaluation of functional outcomes after brachial plexus injury. Quick, T. J. and H. Brown (2020) Level of Evidence : 4 Follow recommendation : 👍 (1/4 thumbs) Type of study : Diagnostic Topic : Assessment of brachial plexus injuries - Motor, sensory, and functional tests to assess brachial plexus injuries This narrative review focused on the available outcomes to assess motor, sensory, pain, and functional impairments in people with brachial plexus injuries. For motor outcomes, the use of dynamometers instead of traditional manual muscle testing has been advised. Thus, they appear to be more reliable and valid to assess muscle strength. Detection of stimuli can be assessed through monofilament testing, which appears to be a good outcome to measure change over time. In addition, the Shape Texture Identification (STI) for stereognosis and the locognosia test for touch localisation can both be used to assess further sensory impairments. Pain can be assessed through multiple outcomes and there is no specific measure for brachial plexus injuries. The visual analogue scale (VAS), the Numerical Rating Scale (NRS), and McGill Pain Questionnaire are only a few of several outcomes available. Finally, the DASH is commonly utilised in brachial plexus injuries, however, it has not been validated in this group of patients. The Brachial plexus Assessment Tool (BrAT) can be used as an alternative to the DASH, however, this is a new scale and requires further research supporting its use. Disclaimer: This publication was reviewed and assessed by one reviewer only and it reflects their interpretation. Readers should come to their own conclusions by reading the original article. Clinical Take Home Message : Based on what we know today, when assessing brachial plexus injuries, motor, sensory, and functional aspects need to be measured. Hand-held dynamometers can be purchased by hand therapists ( roughly $1,600 ) and can provide more valid measurements than manual muscle testing. Monofilaments appear to be a good starting point to assess touch detection. Further assessment of sensibility can be performed through the test for touch localisation , which is free. The Shape Texture Identification test appears to be a great tool but it is not free ( roughly $1,115 ). In regard to pain assessment, we are spoiled for choice. I would personally use both the NRS for pain intensity and the Douleur Neuropathique 4 (DN4), a quick questionnaire that includes three objective tests for the identification of neuropathic pain. URL : https://doi.org/10.1177%2F1753193419879645 Abstract Major nerve injuries such as those of the brachial plexus present a significant challenge for both rehabilitation and evaluation of outcome. With these often complex and multi-faceted injuries, correct selection of outcome measures is important. Healthy nerve function in humans heightens our interactions with the world, creating quality and enjoyment through our experiences of movement and touch. Therefore, assessments should be holistic and representative of all of these features. This article considers the assessment and evaluation of all of the features of nerve injury: sensorimotor, sensation (including that of pain), function and the psychosocial aspects. Current practice is described and combined with clinical experience and research findings to provide suggestions and recommendations for the selection of the most appropriate tools for use with this patient group. publications = Total number of papers citing this research supporting = Citation statements supporting the findings mentioning = Neutral citation statements contrasting = Citation statements not supporting the findings

Translation of Runge's 1873 publication "On the etiology and treatment of writer's cramp": The first description of "tennis elbow". Stegink-Jansen, C. W., B. Jung and J. S. Somerson (2021) Level of Evidence : 5 Follow recommendation : 👍 Type of study : Aetiologic Topic : Lateral epicondylalgia – One of the first articles in scientific literature This paper (published in 2021), translated the original article which was published by Ferdinand Runge in 1873. This was one of the first scientific papers on tennis elbow, which was classified as part of the "writer's cramp" syndromes. In those days, tennis elbow was treated with cauterisation of the skin, galvanic currents, or absolute rest. The choice of treatment was dictated both by the patient's expectations and what Runge suspected to be the problem causing tennis elbow. In particular, Runge changed intervention if the patient lacked confidence in them. In addition, Runge utilised a combination of induction and deductive reasoning in generating the diagnosis and treating the client. Overall they reported being successful in most cases except a minority who would not get better. Disclaimer: This publication was reviewed and assessed by one reviewer only and it reflects their interpretation. Readers should come to their own conclusions by reading the original article. Clinical Take Home Message : Based on what we know today, tennis elbow has likely affected humans for a long time and one of the first published case studies dates back to 1873. Back then like today, it appears that tennis elbow resolves in most people within a short period of time (90% recovery within 12 months without any treatment) . This suggests that independently of the treatment selected (if any) clients with tennis elbow are very likely to get better. Currently, the cheapest conservative treatment (e.g. counterforce brace followed by exercise ) appears to be the most appropriate considering that more expensive interventions (e.g. surgery and PRP do not appear to be more effective than placebo). However, as indicated in this article by Runge, if clients do not have confidence in the intervention that we offer, it may be best to provide some other intervention. This hypothesis on the importance of expectations for therapeutic efficacy is supported by othet evidence . URL : https://doi.org/10.1002/ca.23830 Available through EBSCO Health Databases for PNZ members. Abstract This publication by Dr Ferdinand Runge is ubiquitously credited as first to describe the symptoms, pathology, and treatment of patients with lateral epicondylosis (tennis elbow). However, the main focus of his work was to provide insight into causes of writer's cramp and treatments for the condition, elegantly illustrated in four case reports. This work, recently cited as unavailable, is written in German. Given the high frequency of citations in the English literature, it was considered useful to translate it into English to widen access to a broader readership. The purpose of this project was briefly to introduce the life and clinical expertise of Dr. Ferdinand Runge and the content of his work, followed by a translation of the entire manuscript into English. The paper was translated by the three authors using a process of sequential consensus. All are proficient in German and English, with clinical expertise in both topics. A brief reflection is provided to place Dr Runge's observations, clinical reasoning, and contemporaneously available treatments in the context of current thinking about lateral epicondylalgia. Dr. Runge shares his expertise, carefully reporting pertinent examination findings for each case, sharing hypotheses about the etiology of writer's cramp, and using the effectiveness of his applied treatment as confirmation. He concludes that careful evaluation of the patient's activities that hindered writing prior to the onset of the writer's cramp is key to managing this ailment. The topics addressed in this classic work are still thought-provoking. publications = Total number of papers citing this research supporting = Citation statements supporting the findings mentioning = Neutral citation statements contrasting = Citation statements not supporting the findings

User perspectives on orthoses for thumb carpometacarpal osteoarthritis. Grüschke, J., S., H. Reinders-Messelink, A. van der Vegt and C. van der Sluis (2019) Level of Evidence : N/A Follow recommendation : 👍 Type of study : Therapeutic Topic : Thumb carpo-metacarpal osteoarthritis (OA) and conservative treatment - Qualitative comparison of two thumb orthoses This qualitative study investigated patients' perspectives in relation to a Push-Ortho-Thumb-Brace (PB) and a Custom-Made orthosis (CM) for people with thumb carpo-metacarpal OA. The results showed that on average there was no difference between the two treatments and the pain-relieving effect was 3mm on a 0-100mm Visual Analogue Scale (VAS), similar to 0.3 change on a 0-10 Numerical Rating Scale (NRS). The change in pain was therefore not clinically meaningful, however, some participants reported benefitting from wearing the orthosis. Some reported better functional performance during heavy tasks, others were more comfortable wearing it while resting, and another subgroup used it to prevent further disease progression. While most of the participants considered OA an irreversible process, a subgroup believed in the potential for improvement. Some people reported the orthosis being a nuisance and stopped wearing it altogether. Disclaimer: This publication was reviewed and assessed by one reviewer only and it reflects their interpretation. Readers should come to their own conclusions by reading the original article. Clinical Take Home Message : Based on what we know today, some clients may benefit from thumb orthosis to provide comfort. The orthosis selection does not appear to be as important and patients' preferences should be accommodated. In clients who have trialled an orthosis and find it to be a nuisance, alternative treatments such as exercises should be offered. Hand therapists should have a conversation with those patients who believe that wearing the orthosis prevents OA progression, and explain that there is research suggesting that movement is useful for joint nutrition and health (test your own pain science understanding with this synopsis) . Finally, a reminder that thumb OA orthoses providing biomechanical restrains do not appear to be more effective than placebo orthoses . URL : https://doi.org/10.1016/j.jht.2018.04.006 Abstract Study Design: Qualitative and interpretive description. IntroductionOrthoses are often the first-choice treatment for thumb carpometacarpal osteoarthritis (CMCOA). It is unknown to what extent the orthoses are used in the way intended by health professionals and why patients continue using the orthoses despite minimal pain reduction. Purpose of the Study: The purpose of this study is to investigate user perspectives and experiences with 2 types of CMCOA orthoses. Methods: Semistructured interviews were conducted with 16 individuals with CMCOA who used the Push-Ortho-Thumb-Brace-CMC (Nea International BV, Netherlands) and a custom-made orthosis. The data were analyzed using the phenomenological and the framework approach. Results: Four men and 12 women participated (mean age, 57 years; half of whom were employed). Five central phenomena were identified, explaining the essence of the relation between user and orthosis: the orthosis as stabilizer, tool, healer, preventer, and nuisance. Users mentioned better appearance and the ability to do a variety of activities as advantages of the Push-Ortho-Thumb-Brace-CMC and better support and the ability to do strenuous activities as advantages of the custom-made orthosis. The central phenomena were related to the users' understanding of the disease process and the working mechanism of the orthoses and affected the patterns of usage and orthosis preference. Discussion: It is recommended that the provider recognizes user perspectives and discusses the disease process of CMCOA along with the working mechanism of the orthosis to support therapy adherence. Conclusions: There is a wide variety in usage patterns of the CMCOA orthoses, which are influenced by different user perspectives. publications = Total number of papers citing this research supporting = Citation statements supporting the findings mentioning = Neutral citation statements contrasting = Citation statements not supporting the findings

Non-surgical management of isolated proximal phalangeal fractures with immediate mobilization. Byrne, B., Jacques, A., & Gurfinkel, R. (2020) Level of Evidence : 4 Follow recommendation : 👍 👍 Type of study : Therapeutic Topic : Conservative treatment of proximal phalanx fracture - Splinting and immediate active movement. This single group prospective cohort study assessed the effectiveness of a splinting regime combined with an immediate range of movement exercise program in people with proximal phalanx fractures. Only patients with stable or stable after reduction fractures were included. In addition, angulation on sagittal and coronal plane had to be less than 25° and 10° respectively. Patients were provided with an edema glove and were immobilised in a custom-made hand splint which extended to the pipj and fixated the mcpj in full flexion. During the first week, patients were advised against removing the splint, however, they were encouraged to flex and extend the pipj and dipj hourly. Between week one and four, patients could remove the splint for hand hygiene only and were advised to continue exercising hourly. After four weeks, the splint was removed for light activities and at six weeks the splint was completely removed with progression to full activity as pain allowed. Discharge took place when pain had resolved and when full range of movement was achieved. The results showed that 2.5% of patients lost fracture reduction after one week and required surgical intervention. The median time to discharge was 6 weeks at which point pain had completely resolved and the average pipj flexion range of movement was 94° with 4° of hyperextension. Disclaimer: This publication was reviewed and assessed by one reviewer only and it reflects their interpretation. Readers should come to their own conclusions by reading the original article. Clinical Take Home Message : Based on what we know today, it is possible to treat a proximal phalanx fracture conservatively with an intrinsic plus immobilisation splint and an early controlled active motion exercise program. This approach is applicable if there is less than 25° of sagittal angulation of the fracture and in absence of scissoring of digits. The patient should be monitored closely during the first week after injury as there is a possibility (2.5-9%) of losing fracture stability. Splint weaning should be based on expected healing timeframes as fracture tenderness on palpation does not appear to be a reliable indicator of bone healing . URL : https://doi.org/10.1177%2F1753193419881086 Available through EBSCO Health Databases for PNZ members. Abstract We performed a prospective, observational study using a non-surgical, conservative protocol with immediate mobilization for the treatment of 101 isolated stable or initially unstable proximal phalangeal fractures. The patients were evaluated at the time of discharge from therapy treatment, mean 7 weeks (range 3-15) after conservative treatment. These patients achieved a median proximal interphalangeal joint extension of -4° (IQR 0, -8), a mean total active motion of 253° (SD 20) and minimal pain. We conclude that a non-surgical, conservative protocol can be used for patients with isolated proximal phalangeal fractures without uncorrectable finger rotation or fracture angulation exceeding 25° in the sagittal plane or 10° in the coronal plane following closed reduction. Our data supports that a conservative protocol can be the good option for isolated stable or initially unstable proximal phalangeal fractures. publications = Total number of papers citing this research supporting = Citation statements supporting the findings mentioning = Neutral citation statements contrasting = Citation statements not supporting the findings

Effect of habitual knuckle cracking on hand function. Castellanos, J. and D. Axelrod (1990) Level of Evidence : 2c Follow recommendation : 👍 👍 👍 (3/4 thumbs up) Type of study : Aetiologic Topic : Knuckle cracking - Hand OA This is a cross-sectional study assessing whether habitually cracking knuckles is associated with hand osteoarthritis. A total of 300 participants were included in the study. Of these, 74 reported habitually cracking their knuckles, whilst 226 reported not cracking their knuckles. Participants were included if they were over 45 years old. The assessment included observation of Heberden's and Bouchard's nodes. The results showed that participants who had been cracking their knuckles had been doing so for 18 to 60 years. There was no difference between people cracking or not their knuckles in terms of hand osteoarthritis. Disclaimer: This publication was reviewed and assessed by one reviewer only and it reflects their interpretation. Readers should come to their own conclusions by reading the original article. Clinical Take Home Message : Based on what we know today, cracking your knuckles does not appear to be lead to hand osteoarthritis. If you would like to know what factors currently appear to predict the risk of hand osteoarthritis, have a look at this study . You will also be able to access the prediction model which allows you to calculate your clients/your risk of developing hand OA at 12 years. Open Access URL : http://dx.doi.org/10.1136/ard.49.5.308 Abstract The relation of habitual knuckle cracking to osteoarthrosis with functional impairment of the hand has long been considered an old wives' tale without experimental support. The mechanical sequelae of knuckle cracking have been shown to produce the rapid release of energy in the form of sudden vibratory energy, much like the forces responsible for the destruction of hydraulic blades and ship propellers. To investigate the relation of habitual knuckle cracking to hand function 300 consecutive patients aged 45 years or above and without evidence of neuromuscular, inflammatory, or malignant disease were evaluated for the presence of habitual knuckle cracking and hand arthritis/dysfunction. The age and sex distribution of the patients (74 habitual knuckle crackers, 226 non-knuckle crackers) was similar. There was no increased preponderance of arthritis of the hand in either group; however, habitual knuckle crackers were more likely to have hand swelling and lower grip strength. Habitual knuckle cracking was associated with manual labour, biting of the nails, smoking, and drinking alcohol. It is concluded that habitual knuckle cracking results in functional hand impairment. publications = Total number of papers citing this research supporting = Citation statements supporting the findings mentioning = Neutral citation statements contrasting = Citation statements not supporting the findings

What are the prevalence of and factors independently associated with depression and anxiety among patients with posttraumatic elbow stiffness? A cross-sectional, multicenter study. Liu, W., et al. (2021) Level of Evidence : 4 Follow recommendation : 👍 👍 👍 (3/4 thumbs up) Type of study : Prognostic Topic : Elbow stiffness - Mental health This is a cross-sectional study assessing the relationship between depression and anxiety and impairments associated with elbow stiffness. A total of 108 participants were included. Participants were included if they presented with post-traumatic elbow stiffness and if they had no symptoms of depression and anxiety prior to the injury. Potential participants were excluded if they presented with neurological conditions. General demographic information, clinical measures, and the presence of depression/anxiety (DASS21) were assessed on average 12 months post-injury. The results showed that 20-40% and 25-30% of participants presented with mild-moderate and moderate-severe depression/anxiety respectively. In addition, impairments of elbow flexion, and pain on elbow movement were both factors associated with the increased odds of presenting with depression and anxiety. Disclaimer: This publication was reviewed and assessed by one reviewer only and it reflects their interpretation. Readers should come to their own conclusions by reading the original article. Clinical Take Home Message : Based on what we know today, clients with post-traumatic elbow stiffness are likely to present with depression and anxiety if they present pain on elbow movement and limitations of elbow flexion. The prevalence of these symptoms is reasonably high even at one-year post-injury, and it is, therefore, useful to screen people for these conditions. Thus, the recovery profile of people with mental health issues is worst than people without these conditions . If you would like further information on the treatment of post-traumatic elbow stiffness, refer to this synopsis . URL : https://doi.org/10.1016/j.jse.2021.11.014 Abstract Background: Joint stiffness is a common complication after articular-related trauma in the elbow, resulting in significant limb disability, psychological stress, and a negative impact on daily life. No previous study has reported the impact of posttraumatic elbow stiffness (PTES) on psychological health. This study aims to (1) investigate the depression and anxiety levels and (2) identify factors independently associated with depression and anxiety symptoms in patients with PTES. Methods: A total of 108 patients with PTES presenting to four collaborative municipal hospitals were consecutively enrolled from September to December 2020. Socio-demographic and clinical characteristics were collected through questionnaires and medical records. The Depression Anxiety Stress Scale-21 (DASS21) was used to assess depression and anxiety status. Ordinal logistic regression analysis was performed to identify factors independently associated with depression and anxiety symptoms. Results: The detection rates of mild-to-moderate depression and anxiety are 40.7% and 27.8%, and severe-to-extremely severe levels are 23.1% and 25.9%, respectively. Regression results show that factors independently associated with depression include elbow flexion (OR per 1° loss =1.021, 95% CI: 1.001-1.041, p=0.035), elbow pain on movement (OR per 1 point increase =1.236, 95% CI: 1.029-1.484, p=0.023), family relationship (OR less close / very close =10.059, 95% CI: 2.170-46.633, p=0.003) and self-care ability (OR unable / able =3.858, 95% CI: 1.244-11.961, p=0.019). Factors independently associated with anxiety are elbow flexion (OR per 1° loss =1.031, 95% CI: 1.009-1.052, p=0.005), elbow pain on movement (OR per 1 point increase =1.212, 95% CI: 1.003-1.465, p=0.047) and clinically significant heterotopic ossification (HO) around elbow (OR yes / no =2.344, 95% CI: 1.048-5.243, p=0.038). Conclusion: Patients with PTES exhibit significant depression and anxiety symptoms. Several Socio-demographic and clinical characteristics are independently associated with depression and anxiety levels. Identifying and addressing these factors may be of particular benefit during PTES management. Future research might address whether depression and anxiety affect the outcome after stiff elbow surgery. publications = Total number of papers citing this research supporting = Citation statements supporting the findings mentioning = Neutral citation statements contrasting = Citation statements not supporting the findings

The value added of advanced imaging in the diagnosis and treatment of triangular fibrocartilage complex pathology. Cunningham, D. J., T. S. Pidgeon, E. B. Saltzman, R. C. Mather and D. S. Ruch (2021). Level of Evidence : 3b Follow recommendation : 👍 👍 (2/4 thumbs up) Type of study : Diagnostic Topic : MRI findings ulnar wrist - cost analysis This is study assessed the benefit of adding expensive imaging (e.g. MRI) to history and physical assessment for the treatment of patients with ulnar sided pain. This study was created by modelling the cost vs benefit based on existing evidence. Patients were assumed to be younger than 55 years old, presenting with ulnar sided pain, having subacute to chronic pain, and normal x-rays (e.g. not presenting with positive ulnar variance). The benefits were assessed by predicting changes in QuickDASH under different assessment strategies. The results showed that expensive imaging in addition to history and physical assessment did not provide larger benefits compared to an assessment based on history and physical tests alone (see figure). Disclaimer: This publication was reviewed and assessed by one reviewer only and it reflects their interpretation. Readers should come to their own conclusions by reading the original article. Clinical Take Home Message : Based on what we know today, history, physical assessment, and an x-ray are sufficient to treat people with ulnar sided wrist pain with subacute to acute symptoms. Referral to a hand surgeon is clearly important if symptoms do not resolve with conservative treatment, however, the addition of MRI imaging is unlikely to significantly change the therapeutic strategy and/or its effectiveness. Additional evidence in support of the limited utility of MRI for ulnar sided wrist pain has been shown in a previous study, where elite tennis players with and without ulnar sided wrist pain were assessed . If you would like hints on how to treat ulnar sided wrist pain, have a look at this synopsis . URL : https://doi.org/10.1016/j.jhsa.2021.06.027 Abstract Purpose Pathology of the triangular fibrocartilage complex is a prevalent cause of ulnar-sided wrist pain that presents a diagnostic challenge. We hypothesized that a history and physical examination (H&P) would be more cost-effective alone or with diagnostic injection than with magnetic resonance imaging (MRI) or magnetic resonance arthrogram (MRA) in the diagnosis and treatment of a symptomatic triangular fibrocartilage complex abnormality. Methods A simple-chain decision analysis model was constructed to assess simulated subjects with ulnar-sided wrist pain and normal radiographs using several diagnostic algorithms: H&P alone, H&P + injection, H&P with delayed advanced imaging (MRI or MRA), and H&P + injection with delayed advanced imaging (MRI or MRA). Three years after diagnosis, effectiveness was calculated in Disabilities of the Arm, Shoulder, and Hand–adjusted life years. Costs were extracted from a commercial insurance database using US dollars. A probabilistic sensitivity analysis with 10,000 second-order trials with sampling of parameter distributions was performed. One-way and 2-way sensitivity analyses were performed. Results All strategies had similar mean effectiveness between 2.228 and 2.232 Disabilities of the Arm, Shoulder, and Hand–adjusted life years, with mean costs ranging from $5,584 (H&P alone) to $5,980 (H&P, injection, and MRA). History and physical examination alone or with injection were the most cost-effective strategies. History and physical examination alone was the most preferred diagnostic strategy, though H&P + injection and H&P with delayed MRA were preferred with adjustments in willingness-to-pay and parameter inputs. As willingness-to-pay increased considerably (>$65,000 per Disabilities of the Arm, Shoulder, and Hand–adjusted life year), inclusion of MRA became the most favorable strategy. Conclusions Advanced imaging adds costs and provides minimal increases in effectiveness in the diagnosis and treatment of a symptomatic triangular fibrocartilage complex abnormality. The most cost-effective strategy is H&P, with or without diagnostic injection. Magnetic resonance arthrogram may be favored in situations with a high willingness-to-pay or poor examination characteristics. publications = Total number of papers citing this research supporting = Citation statements supporting the findings mentioning = Neutral citation statements contrasting = Citation statements not supporting the findings

Arthroscopic surgery versus open surgery in lateral epicondylitis in active work population: A comparative study. López-Alameda, S., et al. (2021) Level of Evidence : 2c Follow recommendation : 👍 👍 👍 (3/4 thumbs up) Type of study : Therapeutic Topic : Lateral epicondylalgia - Arthroscopy vs open surgery This is a retrospective study comparing arthroscopy vs open surgery for lateral epicondylalgia. A total of 47 participants were included. Of these, 27 had undergone arthroscopic surgery and 20 open surgery. Participants underwent surgery if they had been unresponsive to three months of conservative treatment. The average time between the onset of pain and surgery in both groups was six months. The QuickDASH was utilised to assess changes in function after surgery. The results showed that there was a clinically significant improvement in both surgical groups, however, there were no differences between the two surgical groups. Disclaimer: This publication was reviewed and assessed by one reviewer only and it reflects their interpretation. Readers should come to their own conclusions by reading the original article. Clinical Take Home Message : Based on what we know today, there is no difference between arthroscopic and open surgery for tennis elbow. Considering that surgery for tennis elbow does not appear to be more effective than placebo and that 90% of people do well at one year, independently of how long they have been having symptoms for , surgery for tennis elbow should probably be left as a last resort. URL : https://doi.org/10.1016/j.jse.2021.11.017 Available through EBSCO Health Databases for PNZ members. Abstract Background: Lateral Epicondylitis is common in workers who perform repetitive movements of the entire upper limb. Approximately 85% to 90% respond satisfactorily to conservative treatment, but in resistant patients, surgical treatment is considered. Classic open surgery is successful between 70% and 97%, similar to more modern techniques such as arthroscopy. We tried to demonstrate the superiority of the Wolf technique in clinical results. The goals of this study were to compare the functional and pain outcomes of arthroscopic surgery with open surgery using fasciotomy as the wolf technique in the treatment of lateral epicondylitis. Methods: This was a retrospective study of 47 working-age patients with resistant lateral epicondylitis: 27 underwent surgery arthroscopically, and 20 underwent open surgery. Pre- and postsurgical VAS and function were assessed using DASH, MEPS and BMRS scales, as well as the return to their previous work and the surgical time. Results: The reduction in VAS showed no statistically significant differences between the groups (5.26 in arthroscopy versus 5.75 in fasciotomy, p = 0.5), QuickDash (19 versus 19.4 with p = 0.9), MEPS (82 versus 81.5 with p = 0.8) or BMRS (81.9 versus 82.6 with p = 0.9). The differences in terms of time off were also not statistically significant. The days of work leave in the arthroscopy group corresponded on average 83.78 days, and in the Wolff group, it corresponded to 89.95 days. The mean surgical time in the arthroscopic intervention group was 44.2 minutes and in the fasciotomy group was 27.5 minutes, showing statistically significant results (p <0.001). Conclusions: Arthroscopic surgery and open surgery in lateral epicondylitis techniques provide similar functional results and pain reduction. publications = Total number of papers citing this research supporting = Citation statements supporting the findings mentioning = Neutral citation statements contrasting = Citation statements not supporting the findings

Persistent tennis elbow symptoms have little prognostic value: A systematic review and meta-analysis. Ikonen, J., et al. (2021) Level of Evidence : 1a Follow recommendation : 👍 👍 👍 👍 (4/4 thumbs up) Type of study : Prognostic Topic : Lateral epicondylalgia – Symptoms duration and recovery This is a systematic review and meta-analysis assessing the recovery trajectory of people with long term lateral epicondylalgia. Only randomised controlled trials (RCT) were included. All the studies were assessed through the Cochrane Risk of Bias criteria. The recovery trajectory was assessed for the control/placebo arm only. Recovery was defined as either "much improvement" or "total resolution of symptoms" at 1, 3, 6, or 12 months. The statistical analyses assessed whether LE symptoms recovery was affected by the duration of symptoms prior to inclusion in the study. The results showed that by 3 months, 50% of participants in the control/placebo arm had recovered, and by 12 months, 90% of them had recovered. The probability of recovery was independent of the duration of symptoms prior to inclusion in the trials. Disclaimer: This publication was reviewed and assessed by one reviewer only and it reflects their interpretation. Readers should come to their own conclusions by reading the original article. Clinical Take Home Message : Based on what we know today, the probability of recovery from tennis elbow does not reduce with longer symptoms duration. This is very encouraging as we can reassure our clients that there is a high probability (90%) of their symptoms to resolve at one year independently of how long they have been suffering from LE. This also suggests that we should avoid referring our clients for surgery just because they have been having pain for a long period of time. Thus, surgery for tennis elbow does not currently appear to be more effective than placebo . URL : https://doi.org/10.1097/corr.0000000000002058 Available through EBSCO Health Databases for PNZ members. Abstract Background: Tennis elbow is a common painful enthesopathy of the lateral elbow that limits upper limb function and frequently results in lost time at work. Surgeons often recommend surgery if symptoms persist despite nonsurgical management, but operations for tennis elbow are inconsistent in their efficacy, and what we know about those operations often derives from observational studies that assume the condition does not continue to improve over time. This assumption is largely untested, and it may not be true; meta-analyzing results from the control arms of tennis elbow studies can help us to evaluate this premise, but to our knowledge, this has not been done. Questions/purposes: The aims of this systematic review were to describe the course of (1) global improvement, (2) pain, and (3) disability in participants who received no active treatment (placebo or no treatment) in published randomized controlled trials (RCTs) on tennis elbow. We also assessed (4) whether the duration of symptoms or placebo effect is associated with differences in symptom trajectories. Methods: We searched MEDLINE, Embase, and CENTRAL from database inception to August 12, 2019, for trials including participants with tennis elbow and a placebo or a no-treatment arm and a minimum follow-up duration of 6 months. There were no language restrictions or exclusion criteria. We extracted global improvement, pain, and disability outcomes. We used the Cochrane Risk of Bias tool to assess the risk of bias of included trials. To estimate the typical course of tennis elbow without active treatment, we pooled global improvement (the proportion of participants who reported feeling much better or completely recovered), mean pain, and mean disability using baseline, 1-month, 3-month, 6-month, and 12-month follow-up data. We transformed pain and disability data from the original papers so that at each timepoint the relevant outcome was expressed as change relative to baseline to account for different baseline values. We used meta-regression to assess whether the placebo effect or duration of symptoms before enrollment was associated with differences in symptom trajectories. We included 24 trials with 1085 participants who received no active treatment. Results: The number of patients who were not improved decreased exponentially over time. The half-life of global improvement was between 2.5 and 3 months (that is, every 2.5 to 3 months, 50% of the remaining symptomatic patients reported complete recovery or greatly improved symptoms). At 1 year, 89% (189 of 213; 95% CI 80% to 97%) of patients experienced global improvement. The mean pain and disability followed a similar pattern, halving every 3 to 4 months. Eighty-eight percent of pain (95% CI 70% to 100%) and 85% of disability (95% CI 60% to 100%) had resolved by 1 year. The mean duration of symptoms before trial enrollment was not associated with differences in symptom trajectories. The trajectories of the no-treatment and placebo arms were similar, indicating that the placebo effect of the studied active treatments likely is negligible. Conclusion: Based on the placebo or no-treatment control arms of randomized trials, about 90% of people with untreated tennis elbow achieve symptom resolution at 1 year. The probability of resolution appears to remain constant throughout the first year of follow-up and does not depend on previous symptom duration, undermining the rationale that surgery is appropriate if symptoms persist beyond a certain point of time. We recommend that clinicians inform people who are frustrated with persisting symptoms that this is not a cause for apprehension, given that spontaneous improvement is about as likely during the subsequent few months as it was early after the symptoms first appeared. Because of the high likelihood of spontaneous recovery, any active intervention needs to be justified by high levels of early efficacy and little or no risk to outperform watchful waiting. Level of Evidence Level I, therapeutic study. publications = Total number of papers citing this research supporting = Citation statements supporting the findings mentioning = Neutral citation statements contrasting = Citation statements not supporting the findings

Dynamic stabilization home exercise program for treatment of thumb carpometacarpal osteoarthritis: A prospective randomized control trial. McVeigh, K. H., et al. (2021) Level of Evidence : 2b Follow recommendation : 👍 👍 👍 (3/4 thumbs up) Type of study : Therapeutic Topic : Thumb osteoarthritis - stabilisation exercises This is a multi-centre randomised controlled study assessing the effect of standard care vs standard care plus thumb stabilisation exercises in participants with thumb osteoarthritis (OA). Participants (N = 64) underwent both a radiological and clinical assessment and were then recruited if they presented with signs and symptoms of thumb OA. Function was measured through the QuickDASH and pain intensity was measured through the Numerical Rating Pain scale (NRS). Other variables such as grip and three different pinch strengths were included in the statistical analyses. The standard care group was provided with a splint and advice on joint protection. The stabilisation exercise group was provided with three exercises shown below (adductor stretching, pinching maintaining an "O" sign, first dorsal interosseus strengthening). These exercises were performed multiple times during the day. The results showed that both groups presented with clinically relevant improvements in pain intensity and close to clinically relevant improvements in the QuickDASH at both six weeks and six months. No statistical or clinically relevant differences were identified between groups. Disclaimer: This publication was reviewed and assessed by one reviewer only and it reflects their interpretation. Readers should come to their own conclusions by reading the original article. Clinical Take Home Message : Based on what we know today, our clients with thumb OA do not benefit from additional stabilisation exercises if we provide them with a multimodal set of interventions already. What seems to be particularly important for people to respond to treatment is their expectations. Thus, in a previous study, positive treatment expectations were associated with better conservative treatment results in people with thumb OA. URL : https://www.sciencedirect.com/science/article/pii/S0894113021000831 Available through The Journal of Hand Therapy for HTNZ members. Available through EBSCO Health Databases for PNZ members. Abstract Study Design: Randomized control trial. Introduction Thumb carpometacarpal (CMC) osteoarthritis (OA) is a common cause of hand pain and disability. Standard conservative therapy (SCT) for thumb CMC OA includes an orthosis and instruction in joint protection, adaptive equipment, and pain relieving modalities. The dynamic stability home exercise (HE) program is complementary conservative therapy designed to strengthen the stabilizing muscles of the thumb CMC. Purpose of the Study: To investigate whether the addition of HE to SCT (SCT+HE) was more effective at reducing pain and disability in thumb CMC OA compared to SCT alone. Methods The study compared 2 groups: SCT and SCT+HE. The SCT group received SCT with in-home pain management instructions, joint protection strategies with adaptive equipment, and a hand-based thumb-spica orthosis. The SCT+HE group received HE program instructions for adductor stretching and opponens and first dorsal interosseous strengthening in addition to SCT. Our primary outcome measure was the numerical rating scale (NRS) with secondary outcome measures of QuickDASH (shortened Disabilities of the Arm, Shoulder and Hand questionnaire), range of motion, grip strength, and pinch strength. Outcome measurements were assessed at first visit, 6 weeks, and 6 months. Results: There was no statistical difference between the 2 groups for NRS and QuickDASH at 6 weeks (P = .28 and P = .36, respectively) or 6 months (P = .52 and P = .97, respectively). However, there was a statistically significant decrease in NRS and QuickDASH scores at 6 weeks and 6 months within both groups. Conclusions: Both SCT and SCT+HE are effective at reducing pain and disability in OA of the thumb CMC joint. Neither therapy program was superior to the other at improving NRS or QuickDASH scores at 6-week or 6-month follow-up. publications = Total number of papers citing this research supporting = Citation statements supporting the findings mentioning = Neutral citation statements contrasting = Citation statements not supporting the findings